Of WNT pathway on post-injury outcome and the cellular mediators involved are not completely understood. Models indicating both positive and negative roles for the WNT pathway depending on the model used, the effect of therapeutic inhibition South C2217A MCN, Nashville, TN 37232, USA, Tel: (615) 936-1098 Fax: (615) 343-702 E-mail: The WNT/β-catenin pathway is temporarily activated in the heart following myocardial infarction (MI). Young, Department of Pathology, Vanderbilt University Medical Center, 1161 21st Ave. †Current affiliation: Department of Veterans Affairs Medical Center, Nashville, TN, USA Research Article Temporary, Systemic Inhibition of the WNT/β- Catenin Pathway promotes Regenerative Cardiac Repair following Myocardial Infarctĭikshya Bastakoty 1 Sarika Saraswati 1† Piyush Joshi 2 James Atkinson 1,3 Igor Feoktistov 4 Jun Liu 5 Jennifer L Harris 5 Pampee P Young 1,3,6* 1Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, USAĢInterdisciplinary Graduate Program, Vanderbilt University Medical Center, Nashville, Tennessee, USAģDepartment of Veterans Affairs Medical Center, Nashville, Tennessee, USAĤDivision of Cardiovascular Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USAĥGenomics Institute of Novartis Research Foundation, San Diego, California, USAĦDepartment of Internal Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA
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